It has been well established that siRNA offtarget effects are caused by the seed sequence of the siRNA (bases 2–8 of the guide strand) 7,10...
【ベストコレクション】 seed region of a crrna 308148-Seed region of a crrna
The seed region is located in the center of the crRNAtarget duplex, where it is more sensitive to mismatches than the nonseed region (Abuday...
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